Arc Institute
Arc Institute is an independent nonprofit biomedical research organization headquartered in Palo Alto, California, co-founded in 2021 by Silvana Konermann (Executive Director), Patrick Hsu (Core Investigator), and Stripe co-founder Patrick Collison. With 300+ staff ("Arconauts") across 9 core laboratories and 5 technology centers, Arc develops AI foundation models for biology that span DNA, RNA, proteins, and single cells. Its flagship releases include Evo (Science, 2024) and Evo 2 (Nature, 2026) — DNA foundation models trained on trillions of nucleotides at single-nucleotide resolution with up to a 1-megabase context; STATE and Stack single-cell foundation models for cellular perturbation and in-context learning; the Arc Virtual Cell Atlas; the SRAgent LLM agents for bioinformatics; and the BINSEQ binary sequencing format. Models are released under Apache 2.0 on GitHub and Hugging Face, with hosted inference for Evo 2 available through NVIDIA BioNeMo and the NVIDIA build.nvidia.com API. Arc is funded by philanthropic donations from Patrick and John Collison, Vitalik Buterin, the Ron Conway family, Dustin Moskovitz, Daniel Gross, Elad Gil, and other technology benefactors; it does not sell APIs, SaaS, or models commercially.
Index entry only — little beyond a description and a link, and nothing machine-readable enough for an agent to act on without a human reading the site first.
API Evangelist profiles Arc Institute the way a machine reads it — 1 machine-readable artifact, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Arc Institute scores 7.9/100 (minimal), with a separate agent-readiness read of 0/100 (human only). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance.
Kin Score
How this is scored →scored 2026-07-27 · rubric v0.5
How we profile Arc Institute
Each block below is one kind of artifact we hold for Arc Institute. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
Security Posture 1
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Every other property we hold for Arc Institute — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Build 2
SDKs, sample code, and the tooling you integrate with
Access & Security 1
Authentication, authorization, and security posture
Learn 1
Tutorials, courses, talks, and written guidance
Company 7
The organization behind the API
Scroll within the panel for all 7 ·
Other 10
Properties that don't map to a standard resource type
Scroll within the panel for all 10 ·
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