Circle Pharma
Circle Pharma is a clinical-stage biopharmaceutical company in South San Francisco, California, developing cell-permeable, orally bioavailable macrocycle therapies for cancer. Founded in 2013 by Matthew P. Jacobson and Scott Lokey out of work on predicting synthetic macrocycle cell permeability, the company applies its proprietary MXMO structure-based design platform to protein-protein interactions that conventional small molecules cannot reach. Its pipeline targets cyclins, the regulators of the cell cycle that drive many cancers: lead program CID-078, a first-in-class oral cyclin A/B RxL inhibitor, is in Phase 1 for advanced solid tumors, followed by a preclinical cyclin D1 RxL inhibitor and undisclosed cyclin programs partnered with Boehringer Ingelheim. Circle Pharma closed a $90M Series D led by The Column Group in 2024 and has an agreement with Eli Lilly to use Lilly TuneLab to strengthen the AI/ML side of the MXMO platform. Circle Pharma runs no developer program and publishes no product API; the only machine-readable surface it exposes is the anonymously readable WordPress REST content API behind circlepharma.com.
Limited machine-readable signal and partial portal coverage — documentation a human can read, but little a machine or agent can consume without scraping.
API Evangelist profiles Circle Pharma the way a machine reads it — 4 machine-readable artifacts across 1 API, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Circle Pharma scores 31.5/100 (thin), with a separate agent-readiness read of 30/100 (agent aware). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance.
Kin Score
How this is scored →scored 2026-08-17 · rubric v0.11.0
Put this on your own site. The badge is drawn live from Circle Pharma's current Kin Score — paste it once and it updates itself every time the score is recomputed. It follows your visitor's light or dark setting, and it links back here so anyone who sees it can read the full breakdown.
<!-- Kin Score · API Evangelist -->
<a href="https://providers.apievangelist.com/providers/circle-pharma/"
title="Circle Pharma on API Evangelist — API profile and Kin Score">
<img src="https://apis.io/badge/circle-pharma.svg"
alt="Circle Pharma Kin Score — API readiness rating by API Evangelist" width="150" height="150" loading="lazy">
</a>[](https://providers.apievangelist.com/providers/circle-pharma/)<!-- Kin Score · API Evangelist -->
<a href="https://providers.apievangelist.com/providers/circle-pharma/"
title="Circle Pharma on API Evangelist — API profile and Kin Score">
<img src="https://apis.io/badge/circle-pharma/card.svg"
alt="Circle Pharma Kin Score — API readiness rating by API Evangelist" width="340" height="120" loading="lazy">
</a>More shapes, themes and sizes → · Score as JSON · How badges work
How we profile Circle Pharma
Each block below is one kind of artifact we hold for Circle Pharma. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
APIs 1
Each API is captured as its own OpenAPI definition — every operation, parameter, and response. This is the single most useful machine-readable description of what an API does, and it's what lets us score, lint, mock, and generate against it without asking the provider for anything.
Individual APIs this provider publishes, each with its own machine-readable definition.
Circle Pharma Content API
The anonymously readable WordPress REST API behind circlepharma.com. It exposes Circle Pharma press releases, publications and in-the-news items (posts), site pages, the media l...
Open Collections 1
Open, tool-agnostic collections carry the same runnable value as Postman without locking you to one client — the portable, forkable form of the same exercise.
Open, tool-agnostic API collections (OpenAPI-derived and Bruno).
Circle Pharma Content API (WordPress REST API)
OPEN COLLECTIONSecurity Posture 2
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Every other property we hold for Circle Pharma — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Agent Surfaces 3
MCP servers, agent skills, and machine-readable catalogs
Design & Contract 5
Pagination, idempotency, versioning, errors, and events
Access & Security 2
Authentication, authorization, and security posture
Operate 3
Status, limits, changes, and where to get help
Commercial 2
Pricing, plans, and the legal terms of use
Company 7
The organization behind the API
Scroll within the panel for all 7 ·
Other 3
Properties that don't map to a standard resource type
← All providers · Data indexed from github.com/api-evangelist/circle-pharma · machine-readable index on apis.io
This is an independent, third-party profile of Circle Pharma, published by API Evangelist. We do not operate, host, resell, or support these APIs, and we are not affiliated with or endorsed by the company unless stated above. Everything here is built from publicly available information — the company's own site, developer portal, documentation, public repositories, and the specifications it publishes for public use. Nothing is obtained by breaching a system, defeating an access control, or using credentials.
The Kin Score and Agent Readiness rating are independently calculated assessments of a company's public API artifacts, scored against a published rubric. They are not certifications, endorsements, security assessments, or audits.
Corrections, re-scores, and removal are free — no partnership or purchase required, and you do not need to justify the request. A removed company is recorded as unrated, never scored zero for having asked. Acknowledgement within one business day; removal within two.
info@apievangelist.com
·
Read the full data-sourcing policy →
On a security or compliance team? Put security in the subject line and
you will get a person, not a form — we will tell you exactly which public URLs this profile was built from.