Cradle
Cradle is a Dutch–Swiss biotechnology software company founded in 2021 with headquarters in Amsterdam and an office in Zurich, building an AI-powered protein engineering platform for industrial biotech and biopharma R&D teams. The platform combines proprietary generative AI models — trained on billions of natural protein sequences and on data produced in Cradle's own Amsterdam wet lab — with a web application and REST API/Python SDK so that scientists can design, simulate, and co-optimize amino-acid sequence variants across multiple measurable properties such as activity, binding affinity, stability, expression, and developability. Core platform capabilities include AI candidate generation, multi-property co-optimization, virtual plate design, experimental data management with full versioning and audit trails, task orchestration (analyze data, diversify, engineer, select, search, train) across modalities including antibodies/mAbs, enzymes, vaccines, therapeutic peptides, and food ingredients, plus a Custom Predictors framework letting customers plug in their own ML models. Cradle is sold as enterprise SaaS to R&D organizations — disclosed customers and partners include Johnson & Johnson Janssen, Bayer, Novozymes/Novonesis, and Twist Bioscience, with the platform serving six of the top 25 global pharma companies and over 50 active R&D programs. The company has raised approximately $115M to date across a seed round (Index Ventures, 2022), a $24M Series A (Index Ventures, 2023), and a $73M Series B (IVP, 2024). Co-founders are Stef van Grieken (CEO), Jelle Prins, Elise de Reus, Eli Bixby, and Harmen van Rossum.
Index entry only — little beyond a description and a link, and nothing machine-readable enough for an agent to act on without a human reading the site first.
API Evangelist profiles Cradle the way a machine reads it — 2 machine-readable artifacts across 1 API, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Cradle scores 10.1/100 (minimal), with a separate agent-readiness read of 0/100 (human only). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance. Every facet and dimension name is a link: it opens that measurement's page on APIs.io, where the rating runs across the whole catalog — the exact checks that feed it, how every profiled provider distributes on it, and who is at the top of it.
Kin Score
How this is scored →scored 2026-09-08 · rubric v0.20.0
Put this on your own site. The badge is drawn live from Cradle's current Kin Score — paste it once and it updates itself every time the score is recomputed. It follows your visitor's light or dark setting, and it links back here so anyone who sees it can read the full breakdown.
<!-- Kin Score · API Evangelist -->
<a href="https://providers.apievangelist.com/providers/cradle-bio/"
title="Cradle on API Evangelist — API profile and Kin Score">
<img src="https://apis.io/badge/cradle-bio.svg"
alt="Cradle Kin Score — API readiness rating by API Evangelist" width="150" height="150" loading="lazy">
</a>[](https://providers.apievangelist.com/providers/cradle-bio/)<!-- Kin Score · API Evangelist -->
<a href="https://providers.apievangelist.com/providers/cradle-bio/"
title="Cradle on API Evangelist — API profile and Kin Score">
<img src="https://apis.io/badge/cradle-bio/card.svg"
alt="Cradle Kin Score — API readiness rating by API Evangelist" width="340" height="120" loading="lazy">
</a>More shapes, themes and sizes → · Score as JSON · How badges work
How we profile Cradle
Each block below is one kind of artifact we hold for Cradle. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
APIs 1
Each API is captured as its own OpenAPI definition — every operation, parameter, and response. This is the single most useful machine-readable description of what an API does, and it's what lets us score, lint, mock, and generate against it without asking the provider for anything.
Individual APIs this provider publishes, each with its own machine-readable definition.
Cradle Platform API
The Cradle Platform API is an enterprise REST API for programmatic access to Cradle's AI-driven protein engineering platform. It is organized under per-workspace v2 endpoints an...
Security Posture 1
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Every other property we hold for Cradle — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Documentation 2
Reference material describing how the API behaves
Build 3
SDKs, sample code, and the tooling you integrate with
Access & Security 2
Authentication, authorization, and security posture
Company 6
The organization behind the API
Other 7
Properties that don't map to a standard resource type
Scroll within the panel for all 7 ·
← All providers · Data indexed from github.com/api-evangelist/cradle-bio · machine-readable index on apis.io
This is an independent, third-party profile of Cradle, published by API Evangelist. We do not operate, host, resell, or support these APIs, and we are not affiliated with or endorsed by the company unless stated above. Everything here is built from publicly available information — the company's own site, developer portal, documentation, public repositories, and the specifications it publishes for public use. Nothing is obtained by breaching a system, defeating an access control, or using credentials.
The Kin Score and Agent Readiness rating are independently calculated assessments of a company's public API artifacts, scored against a published rubric. They are not certifications, endorsements, security assessments, or audits.
Corrections, re-scores, and removal are free — no partnership or purchase required, and you do not need to justify the request. A removed company is recorded as unrated, never scored zero for having asked. Acknowledgement within one business day; removal within two.
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