Dyno
Dyno Therapeutics is an AI and biotechnology company building high-performance gene delivery technologies to unlock the potential of next-generation genetic medicine. Using its CapsidMap platform, which combines machine learning with high-throughput in vivo measurement, Dyno designs novel adeno-associated virus (AAV) capsids with improved tissue targeting, immune evasion, manufacturability, and payload capacity. Alongside its capsid partnerships, Dyno operates a public developer platform — Dyno Psi-Phi at design.dynotx.com — that exposes a REST API for agentic protein design: submit structure-prediction, inverse-folding and binder-scoring jobs against GPU-backed open models (AlphaFold2, ESMFold, ProteinMPNN, Boltz, ESM-2, RFDiffusion3, BoltzGen, OpenFold3), track job status, and retrieve scored results. The platform ships a first-party Python CLI (dyno-phi), an MIT-licensed open-source repository, and a provider-published Claude Code Agent Skill. Founded on research from George Church's lab at Harvard, Dyno is headquartered in Watertown, Massachusetts, and is an a16z Bio+Health portfolio company.
Real signal across most facets with visible, nameable gaps — the contract exists but is thin, or the portal is good while governance and commercial terms are absent.
API Evangelist profiles Dyno the way a machine reads it — 22 machine-readable artifacts across 2 APIs, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Dyno scores 48.3/100 (developing), with a separate agent-readiness read of 29/100 (agent ready). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance. Every facet and dimension name is a link: it opens that measurement's page on APIs.io, where the rating runs across the whole catalog — the exact checks that feed it, how every profiled provider distributes on it, and who is at the top of it.
Kin Score
How this is scored →scored 2026-09-08 · rubric v0.20.0
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How we profile Dyno
Each block below is one kind of artifact we hold for Dyno. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
APIs 17
Each API is captured as its own OpenAPI definition — every operation, parameter, and response. This is the single most useful machine-readable description of what an API does, and it's what lets us score, lint, mock, and generate against it without asking the provider for anything.
Individual APIs this provider publishes, each with its own machine-readable definition.
Dyno Admin API
The admin API from Dyno — 5 operation(s) for admin.
Dyno Agents API
The agents API from Dyno — 3 operation(s) for agents.
Dyno Artifacts API
The Artifacts API from Dyno — 2 operation(s) for artifacts.
Dyno Assets API
The assets API from Dyno — 6 operation(s) for assets.
Dyno Auth API
The auth API from Dyno — 2 operation(s) for auth.
Dyno Datasets API
The datasets API from Dyno — 4 operation(s) for datasets.
Dyno Files API
The files API from Dyno — 2 operation(s) for files.
Dyno Health API
The Health API from Dyno — 1 operation(s) for health.
Dyno Ingest API
The ingest API from Dyno — 5 operation(s) for ingest.
Dyno Jobs API
The jobs API from Dyno — 7 operation(s) for jobs.
Dyno Phi API
The Phi API from Dyno — 2 operation(s) for phi.
Dyno Protocols API
The protocols API from Dyno — 7 operation(s) for protocols.
Dyno Research Notes API
The research-notes API from Dyno — 1 operation(s) for research-notes.
Dyno Runs API
The Runs API from Dyno — 4 operation(s) for runs.
Dyno Tools API
The tools API from Dyno — 3 operation(s) for tools.
Dyno Tutorial API
The tutorial API from Dyno — 1 operation(s) for tutorial.
Dyno Workflows API
The workflows API from Dyno — 9 operation(s) for workflows.
Scroll within the panel for all 17 ·
Open Collections 1
Open, tool-agnostic collections carry the same runnable value as Postman without locking you to one client — the portable, forkable form of the same exercise.
Open, tool-agnostic API collections (OpenAPI-derived and Bruno).
Phi — Protein Design API
OPEN COLLECTIONPricing Plans 1
Pricing is part of the interface. Machine-readable plans tell you what a tier costs and includes before you commit — one of the things the Kin Score reads for access clarity — renamed from commercial clarity in rubric 0.12, because a free statutory interface has access terms and no commercial ones.
Published pricing tiers and plan structures.
Dyno Plans Pricing
PLANSRate Limits 1
Rate limits are the difference between a demo that works and a production integration that doesn't fall over. Publishing them is an operational-transparency signal — and a hard requirement for any agent that plans its own throughput.
Documented rate limits and quota policies.
Dyno Rate Limits
RATE LIMITSSecurity Posture 2
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Every other property we hold for Dyno — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Get Started 4
Portal, sign-up, and the first successful call
Documentation 2
Reference material describing how the API behaves
Agent Surfaces 3
MCP servers, agent skills, and machine-readable catalogs
Design & Contract 5
Pagination, idempotency, versioning, errors, and events
Build 5
SDKs, sample code, and the tooling you integrate with
Access & Security 2
Authentication, authorization, and security posture
Operate 3
Status, limits, changes, and where to get help
Commercial 4
Pricing, plans, and the legal terms of use
Company 2
The organization behind the API
Other 4
Properties that don't map to a standard resource type
← All providers · Data indexed from github.com/api-evangelist/dyno · machine-readable index on apis.io
This is an independent, third-party profile of Dyno, published by API Evangelist. We do not operate, host, resell, or support these APIs, and we are not affiliated with or endorsed by the company unless stated above. Everything here is built from publicly available information — the company's own site, developer portal, documentation, public repositories, and the specifications it publishes for public use. Nothing is obtained by breaching a system, defeating an access control, or using credentials.
The Kin Score and Agent Readiness rating are independently calculated assessments of a company's public API artifacts, scored against a published rubric. They are not certifications, endorsements, security assessments, or audits.
Corrections, re-scores, and removal are free — no partnership or purchase required, and you do not need to justify the request. A removed company is recorded as unrated, never scored zero for having asked. Acknowledgement within one business day; removal within two.
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