Iambic Therapeutics
Iambic Therapeutics is a San Diego, California AI-driven drug discovery company founded in 2019 by Thomas Miller (CEO) and Fred Manby (CTO) that designs small-molecule therapeutics for oncology and other indications. Iambic builds proprietary AI models for drug discovery, including Enchant, a multimodal transformer that predicts clinical properties (pharmacokinetics, cellular and biochemical activity) of candidate molecules from early discovery data, and NeuralPLexer (now NeuralPLexer3), a flow-based generative model for protein-ligand complex structure prediction used to identify cryptic pockets and guide structure-based design. Both lines of work have been published at venues including NeurIPS 2025. The company's internal pipeline is oncology-led: IAM1363, a brain-penetrant selective HER2 / HER2-mutant inhibitor, completed Phase 1/1b dose escalation in 2025 and is in dose optimization with clinical activity reported at ESMO 2025; IAM-K1 (KIF18A) and IAM-C1 (CDK2/4) are preclinical, alongside undisclosed neurology, gastrointestinal, and inflammation discovery programs. In February 2026 Iambic announced a discovery and technology collaboration with Takeda worth up to ~$1.7B plus royalties, following a $100M+ private financing in November 2025 and total disclosed funding of approximately $334M. The company has been named to the CNBC Disruptor 50 list in 2025 and 2026 and has signaled intent to access public markets, including via a SPAC. Iambic's public GitHub footprint is limited to np-bench, a BSD-3 benchmark library for 3D biomolecular structure prediction; the underlying NeuralPLexer and Enchant models are proprietary and there is no public developer API, SDK, or commercial platform offering.
Index entry only — little beyond a description and a link, and nothing machine-readable enough for an agent to act on without a human reading the site first.
API Evangelist profiles Iambic Therapeutics the way a machine reads it — 1 machine-readable artifact, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Iambic Therapeutics scores 7.9/100 (minimal), with a separate agent-readiness read of 0/100 (human only). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance.
Kin Score
How this is scored →scored 2026-07-27 · rubric v0.5
How we profile Iambic Therapeutics
Each block below is one kind of artifact we hold for Iambic Therapeutics. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
Security Posture 1
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Every other property we hold for Iambic Therapeutics — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Build 1
SDKs, sample code, and the tooling you integrate with
Access & Security 1
Authentication, authorization, and security posture
Operate 1
Status, limits, changes, and where to get help
Company 7
The organization behind the API
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Other 9
Properties that don't map to a standard resource type
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