Kartos Therapeutics
Kartos Therapeutics, Inc. is a privately held, clinical-stage biopharmaceutical company headquartered at 275 Shoreline Drive, Redwood City, California, developing navtemadlin (KRT-232), an orally administered, potent and selective small-molecule inhibitor of MDM2. The company was founded in 2016 by Wayne Rothbaum, president of Quogue Capital and co-founder of Acerta Pharma, around an MDM2 inhibitor in-licensed from Amgen. Navtemadlin blocks the MDM2 protein that suppresses p53, restoring p53 function in tumours that retain wild-type TP53 and driving cell-cycle arrest through p21 and apoptosis through pro-apoptotic Bcl-2 family proteins. The clinical programme is centred on myelofibrosis and includes the enrolling global Phase 3 POIESIS trial of navtemadlin added to ruxolitinib (NCT06479135), the Phase 1b/2 KRT-232-109 combination study (NCT04485260), and the completed Phase 3 BOREAS study of navtemadlin versus best available therapy in JAK-inhibitor relapsed or refractory myelofibrosis (NCT03662126), with reported activity also in acute myeloid leukaemia and Merkel cell carcinoma. Kartos is led by CEO Jesse McGreivy, MD, with Srdan Verstovsek, MD, PhD as chief medical officer, and is backed by Quogue Capital, OrbiMed Advisors, Amgen, SR One, Fidelity, BlackRock, T. Rowe Price, Invus and Soleus Capital. Kartos Therapeutics runs no developer program and publishes no product API, no developer portal and no API documentation; the only machine-readable surface reachable without credentials is the WordPress REST content API behind kartosthera.com, catalogued here.
More than an index entry, but the surface is still mostly links rather than artifacts — the cohort most likely to move a full band from modest, well-targeted work.
API Evangelist profiles Kartos Therapeutics the way a machine reads it — 17 machine-readable artifacts across 7 APIs, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Kartos Therapeutics scores 19.7/100 (emerging), with a separate agent-readiness read of 33/100 (agent aware). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance.
Kin Score
How this is scored →scored 2026-08-17 · rubric v0.11.0
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How we profile Kartos Therapeutics
Each block below is one kind of artifact we hold for Kartos Therapeutics. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
APIs 7
Each API is captured as its own OpenAPI definition — every operation, parameter, and response. This is the single most useful machine-readable description of what an API does, and it's what lets us score, lint, mock, and generate against it without asking the provider for anything.
Individual APIs this provider publishes, each with its own machine-readable definition.
Kartos Therapeutics Content API
Published pages and the site-wide search index.
Kartos Therapeutics Discovery API
The route index and namespace descriptors the site publishes about itself.
Kartos Therapeutics Media API
The media library — scientific figures, investor logos and presentation PDFs.
Kartos Therapeutics Oembed API
The oEmbed 1.0 provider endpoint for kartosthera.com URLs.
Kartos Therapeutics People API
The leadership, board and advisor team custom post type.
Kartos Therapeutics Science API
The navtemadlin congress presentations and publications custom post type.
Kartos Therapeutics Taxonomy API
Registered post types, statuses, taxonomies and terms.
Scroll within the panel for all 7 ·
Open Collections 8
Open, tool-agnostic collections carry the same runnable value as Postman without locking you to one client — the portable, forkable form of the same exercise.
Open, tool-agnostic API collections (OpenAPI-derived and Bruno).
API Collection
OPEN COLLECTIONKartos Therapeutics Content API
OPEN COLLECTIONKartos Therapeutics Content Discovery API
OPEN COLLECTIONKartos Therapeutics Content Media API
OPEN COLLECTIONKartos Therapeutics Content Oembed API
OPEN COLLECTIONKartos Therapeutics Content People API
OPEN COLLECTIONKartos Therapeutics Content Science API
OPEN COLLECTIONKartos Therapeutics Content Taxonomy API
OPEN COLLECTIONScroll within the panel for all 8 ·
Security Posture 2
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Every other property we hold for Kartos Therapeutics — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Agent Surfaces 3
MCP servers, agent skills, and machine-readable catalogs
Design & Contract 5
Pagination, idempotency, versioning, errors, and events
Access & Security 2
Authentication, authorization, and security posture
Operate 2
Status, limits, changes, and where to get help
Commercial 1
Pricing, plans, and the legal terms of use
Company 3
The organization behind the API
Other 6
Properties that don't map to a standard resource type
← All providers · Data indexed from github.com/api-evangelist/kartos-therapeutics · machine-readable index on apis.io
This is an independent, third-party profile of Kartos Therapeutics, published by API Evangelist. We do not operate, host, resell, or support these APIs, and we are not affiliated with or endorsed by the company unless stated above. Everything here is built from publicly available information — the company's own site, developer portal, documentation, public repositories, and the specifications it publishes for public use. Nothing is obtained by breaching a system, defeating an access control, or using credentials.
The Kin Score and Agent Readiness rating are independently calculated assessments of a company's public API artifacts, scored against a published rubric. They are not certifications, endorsements, security assessments, or audits.
Corrections, re-scores, and removal are free — no partnership or purchase required, and you do not need to justify the request. A removed company is recorded as unrated, never scored zero for having asked. Acknowledgement within one business day; removal within two.
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