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Manus Bio website screenshot

Manus Bio

Manus Bio Inc. (trading as "Manus", the BioAlternatives Company) is a Cambridge, Massachusetts industrial biotechnology company founded in 2011 out of MIT by Dr. Aji Parayil and Dr. Greg Stephanopoulos. Manus engineers microbial cell factories and precision-fermentation processes so that complex molecules normally obtained through petrochemical synthesis, agricultural extraction, or animal husbandry can be produced by fermentation instead - what the company calls bioalternatives. Its commercialized products include the first U.S. commercial-scale monk fruit sweetener (produced at its Augusta, Georgia BioFacility), the Yume M stevia Reb M sweetener co-developed with Tate & Lyle, citrus-derived aroma ingredients (Nootkatone 70, Valencene 80, BioNootkatone) for Givaudan, and an artemisinin antimalarial program funded by HHS/ASPR. It sells scale-up services through its BioAccelerator and BioManufacturing programs (protein engineering, strain development, bioprocess development from 250 ml to 3,000 L, pilot-scale and biomanufacturing). In April 2025 Manus merged with genome-engineering company Inscripta, adding whole-genome editing technology and the MAD7 CRISPR nuclease licensing program; inscripta.com is now a redirect notice. Manus is a manufacturer of physical ingredients and a contract development and manufacturing organization - it sells molecules and services, not software. It publishes no public API, developer portal, SDK, webhook surface, or machine-readable specification of any kind, and its computational and AI-driven enzyme-engineering tools are internal capabilities that support its services rather than a customer-facing platform.

human only

Index entry only — little beyond a description and a link, and nothing machine-readable enough for an agent to act on without a human reading the site first.

Kin Score

API Evangelist profiles Manus Bio the way a machine reads it — 1 machine-readable artifact, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.

Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Manus Bio scores 11.4/100 (minimal), with a separate agent-readiness read of 0/100 (human only). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.

No API surface

Why this profile is thin

Manus sells fermentation-produced ingredients and contract biomanufacturing services, not software; its Webflow marketing site returns 404 for every contract-discovery path, no api./docs./developer. subdomain resolves, and the github.com/ManusBio organization has zero public repositories.

This is an honest zero, not a gap in our research. Manus Bio does not appear to expose an API, so there is nothing here for us to index and nothing for them to fix.

What we probed
  • https://www.manusbio.com/openapi.jsonHTTP 404
  • https://www.manusbio.com/llms.txtHTTP 404
  • https://www.manusbio.com/.well-known/security.txtHTTP 404
  • https://www.manusbio.com/.well-known/agent-card.jsonHTTP 404
  • https://www.manusbio.com/.well-known/agent.jsonHTTP 404
  • https://www.manusbio.com/sitemap.xmlHTTP 200
  • https://www.inscripta.com/HTTP 200
  • https://api.github.com/orgs/manusbioHTTP 200

Checked 2026-08-04. If this is out of date, tell us on the provider's repo and we will re-run the profile.

Kin Score

This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance.

Kin Score Kin Score How this is scored →
scored 2026-08-17 · rubric v0.11.0
Composite quality — 11.4/100 · minimal
Contract Quality 0.0 / 25
Developer Ergonomics 0.4 / 20
Commercial Clarity 4.2 / 20
Operational Transparency 0.7 / 13
Governance 0.0 / 12
Discoverability 5.0 / 10
Regulatory · Health 2.6 / 15
Agent readiness — 0/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 10
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 0 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Manus Bio Kin Score — API readiness rating by API Evangelist

Put this on your own site. The badge is drawn live from Manus Bio's current Kin Score — paste it once and it updates itself every time the score is recomputed. It follows your visitor's light or dark setting, and it links back here so anyone who sees it can read the full breakdown.

<!-- Kin Score · API Evangelist -->
<a href="https://providers.apievangelist.com/providers/manus-bio/"
   title="Manus Bio on API Evangelist — API profile and Kin Score">
  <img src="https://apis.io/badge/manus-bio.svg"
       alt="Manus Bio Kin Score — API readiness rating by API Evangelist" width="150" height="150" loading="lazy">
</a>

More shapes, themes and sizes → · Score as JSON · How badges work

How we profile Manus Bio

Each block below is one kind of artifact we hold for Manus Bio. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Manus Bio Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Resources

Every other property we hold for Manus Bio — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.

Build 1

SDKs, sample code, and the tooling you integrate with

Access & Security 1

Authentication, authorization, and security posture

Operate 1

Status, limits, changes, and where to get help

Commercial 2

Pricing, plans, and the legal terms of use

Company 4

The organization behind the API

← All providers · Data indexed from github.com/api-evangelist/manus-bio · machine-readable index on apis.io

Where this information came from

This is an independent, third-party profile of Manus Bio, published by API Evangelist. We do not operate, host, resell, or support these APIs, and we are not affiliated with or endorsed by the company unless stated above. Everything here is built from publicly available information — the company's own site, developer portal, documentation, public repositories, and the specifications it publishes for public use. Nothing is obtained by breaching a system, defeating an access control, or using credentials.

The Kin Score and Agent Readiness rating are independently calculated assessments of a company's public API artifacts, scored against a published rubric. They are not certifications, endorsements, security assessments, or audits.

Corrections, re-scores, and removal are free — no partnership or purchase required, and you do not need to justify the request. A removed company is recorded as unrated, never scored zero for having asked. Acknowledgement within one business day; removal within two.

info@apievangelist.com · Read the full data-sourcing policy →
On a security or compliance team? Put security in the subject line and you will get a person, not a form — we will tell you exactly which public URLs this profile was built from.