Metacrine
Metacrine, Inc. was a San Diego, California clinical-stage biopharmaceutical company founded in 2014 to develop differentiated therapies for liver and gastrointestinal disease. It built a proprietary farnesoid X receptor (FXR) platform on a distinct chemical scaffold and advanced two oral, once-daily FXR agonists — MET409 and MET642 — through Phase 1 and Phase 2 trials in non-alcoholic steatohepatitis (NASH), alongside exploratory work in inflammatory bowel disease. Backed by ARCH Venture Partners, Polaris Partners, venBio and EcoR1 Capital, it raised a $36M round in 2015 and a $65M Series C in June 2018 before pricing an initial public offering on 2020-09-15 of 6,540,000 shares at $13.00, for roughly $85.0M gross, and listing on the Nasdaq Capital Market as MTCR. Equillium, Inc. agreed to acquire the company in an all-stock transaction announced 2022-09-06, but the two mutually terminated the merger agreement on 2022-12-23. The board approved a Plan of Dissolution on 2023-01-24; Nasdaq issued a minimum-bid-price delisting notice on 2023-01-31, trading was suspended on 2023-02-09 and delisting took effect 2023-03-13; the FXR program assets were sold under a February 2023 term sheet for up to $4.0M in cash plus assumed liabilities; stockholders approved the dissolution on 2023-03-23; and the company filed a Certificate of Dissolution with the Delaware Secretary of State on 2023-03-24, effective on filing under DGCL Section 275. Metacrine was a drug developer, not a software vendor, and it never published a developer program, public API, SDK, webhook surface, or machine-readable specification of any kind. Its domain metacrine.com has since lapsed and is parked. This profile is retained as a historical record; there is no API surface to enrich.
Index entry only — little beyond a description and a link, and nothing machine-readable enough for an agent to act on without a human reading the site first.
Metacrine is tracked in the API Evangelist network. This page is the human-readable profile that sits on top of the machine-readable index we maintain at apis.io.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Metacrine scores 1.8/100 (minimal), with a separate agent-readiness read of 0/100 (human only). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Why this profile is thin
Metacrine, Inc. was a clinical-stage biopharmaceutical developer that never shipped software, and it filed a Certificate of Dissolution with the Delaware Secretary of State on 2023-03-24; its original domain metacrine.com has since lapsed onto Network Solutions' PENDINGRENEWALDELETION nameservers and a Media.net parking wildcard that answers HTTP 200 with the same 122-byte "Error. Page cannot be displayed" stub for every path and every subdomain, including a control path that cannot exist, so none of those 200s is a document.
This is an honest zero, not a gap in our research. Metacrine does not appear to expose an API, so there is nothing here for us to index and nothing for them to fix.
What we probed
https://www.sec.gov/Archives/edgar/data/1634379/000119312523079293/d453945d8k.htm→ HTTP 200http://metacrine.com/→ HTTP 200http://metacrine.com/openapi.json→ HTTP 200http://metacrine.com/.well-known/agent-card.json→ HTTP 200http://metacrine.com/control-path-does-not-exist-98765→ HTTP 200https://metacrine.com/→ HTTP 0https://api.github.com/orgs/metacrine→ HTTP 404https://registry.npmjs.org/metacrine→ HTTP 404https://forgeglobal.com/metacrine_stock/→ HTTP 403
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance. Every facet and dimension name is a link: it opens that measurement's page on APIs.io, where the rating runs across the whole catalog — the exact checks that feed it, how every profiled provider distributes on it, and who is at the top of it.
Kin Score
How this is scored →scored 2026-09-01 · rubric v0.18.0
Put this on your own site. The badge is drawn live from Metacrine's current Kin Score — paste it once and it updates itself every time the score is recomputed. It follows your visitor's light or dark setting, and it links back here so anyone who sees it can read the full breakdown.
<!-- Kin Score · API Evangelist -->
<a href="https://providers.apievangelist.com/providers/metacrine/"
title="Metacrine on API Evangelist — API profile and Kin Score">
<img src="https://apis.io/badge/metacrine.svg"
alt="Metacrine Kin Score — API readiness rating by API Evangelist" width="150" height="150" loading="lazy">
</a>[](https://providers.apievangelist.com/providers/metacrine/)<!-- Kin Score · API Evangelist -->
<a href="https://providers.apievangelist.com/providers/metacrine/"
title="Metacrine on API Evangelist — API profile and Kin Score">
<img src="https://apis.io/badge/metacrine/card.svg"
alt="Metacrine Kin Score — API readiness rating by API Evangelist" width="340" height="120" loading="lazy">
</a>More shapes, themes and sizes → · Score as JSON · How badges work
Resources
Every other property we hold for Metacrine — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Agent Surfaces 1
MCP servers, agent skills, and machine-readable catalogs
Other 1
Properties that don't map to a standard resource type
Metacrine is in the network as a tracked entity. We haven't yet indexed a public API surface for it — when one is published, the artifacts, score, and agent-readiness read will appear here automatically. The source repository is where that profile is built.
← All providers · Data indexed from github.com/api-evangelist/metacrine · machine-readable index on apis.io
This is an independent, third-party profile of Metacrine, published by API Evangelist. We do not operate, host, resell, or support these APIs, and we are not affiliated with or endorsed by the company unless stated above. Everything here is built from publicly available information — the company's own site, developer portal, documentation, public repositories, and the specifications it publishes for public use. Nothing is obtained by breaching a system, defeating an access control, or using credentials.
The Kin Score and Agent Readiness rating are independently calculated assessments of a company's public API artifacts, scored against a published rubric. They are not certifications, endorsements, security assessments, or audits.
Corrections, re-scores, and removal are free — no partnership or purchase required, and you do not need to justify the request. A removed company is recorded as unrated, never scored zero for having asked. Acknowledgement within one business day; removal within two.
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