One Codex
One Codex is a microbial genomics data platform for fast, reproducible microbiome sequencing and analysis. Its cloud platform pairs the "world's largest microbial reference database" with automated shotgun and amplicon pipelines, sample management, and collaboration for academic institutions, biotech companies, and clinical laboratories. Beyond the web application, One Codex exposes a RESTful JSON API (self-described with JSON Schema) covering samples, analyses, classifications, panels, alignments, MLST, functional profiles, jobs/workflows, projects, metadata, tags, documents, sequencing batches, events, and webhooks — plus an official `onecodex` Python client and CLI. The company also offers a Genome Library and end-to-end microbiome sequencing services. One Codex is a portfolio company of DCVC.
Real signal across most facets with visible, nameable gaps — the contract exists but is thin, or the portal is good while governance and commercial terms are absent.
API Evangelist profiles One Codex the way a machine reads it — 31 machine-readable artifacts across 25 APIs, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — One Codex scores 59.6/100 (developing), with a separate agent-readiness read of 75/100 (agent native). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance.
Kin Score
How this is scored →scored 2026-07-27 · rubric v0.5
How we profile One Codex
Each block below is one kind of artifact we hold for One Codex. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
APIs 25
Each API is captured as its own OpenAPI definition — every operation, parameter, and response. This is the single most useful machine-readable description of what an API does, and it's what lets us score, lint, mock, and generate against it without asking the provider for anything.
Individual APIs this provider publishes, each with its own machine-readable definition.
One Codex Account API
The Account API from One Codex — 1 operation(s) for account.
One Codex Alignments API
The Alignments API from One Codex — 9 operation(s) for alignments.
One Codex Analyses API
The Analyses API from One Codex — 9 operation(s) for analyses.
One Codex Annotation Sets API
The Annotation Sets API from One Codex — 4 operation(s) for annotation sets.
One Codex Assemblies API
The Assemblies API from One Codex — 3 operation(s) for assemblies.
One Codex Assets API
The Assets API from One Codex — 5 operation(s) for assets.
One Codex Classifications API
The Classifications API from One Codex — 11 operation(s) for classifications.
One Codex Controls API
The Controls API from One Codex — 9 operation(s) for controls.
One Codex Documents API
The Documents API from One Codex — 9 operation(s) for documents.
One Codex Events API
The Events API from One Codex — 2 operation(s) for events.
One Codex Functional Profiles API
The Functional Profiles API from One Codex — 10 operation(s) for functional profiles.
One Codex Genomes API
The Genomes API from One Codex — 2 operation(s) for genomes.
One Codex Jobs API
The Jobs API from One Codex — 4 operation(s) for jobs.
One Codex Metadata API
The Metadata API from One Codex — 2 operation(s) for metadata.
One Codex Mlsts API
The Mlsts API from One Codex — 9 operation(s) for mlsts.
One Codex Panels API
The Panels API from One Codex — 9 operation(s) for panels.
One Codex Projects API
The Projects API from One Codex — 7 operation(s) for projects.
One Codex Reports API
The Reports API from One Codex — 9 operation(s) for reports.
One Codex Samples API
The Samples API from One Codex — 11 operation(s) for samples.
One Codex Sequencing API
The Sequencing API from One Codex — 4 operation(s) for sequencing.
One Codex Tags API
The Tags API from One Codex — 2 operation(s) for tags.
One Codex Taxa API
The Taxa API from One Codex — 5 operation(s) for taxa.
One Codex Users API
The Users API from One Codex — 2 operation(s) for users.
One Codex Webhooks API
The Webhooks API from One Codex — 2 operation(s) for webhooks.
One Codex Workflows API
The Workflows API from One Codex — 9 operation(s) for workflows.
Scroll within the panel for all 25 ·
MCP Servers 1
Model Context Protocol servers expose these APIs directly to AI agents. We profile them because agent-native access is the fastest-growing way this provider's capabilities actually get used.
Model Context Protocol servers that expose these APIs to AI agents.
one-codex-mcp.yml
MCP SERVEREvent Specifications 1
Not every API is request/response. AsyncAPI describes the event-driven and streaming side — the webhooks and channels — so the asynchronous half of the interface is documented the same way the synchronous half is.
AsyncAPI definitions for this provider's event-driven and streaming APIs.
One Codex Webhooks
ASYNCAPISecurity Posture 3
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Agentic Access 1
An x-agentic-access contract marks which operations are safe for an agent to run on its own and which need a human in the loop. It is the difference between an API an agent can use and one it can use safely.
Recommended x-agentic-access execution contracts for AI agents.
Resources
Every other property we hold for One Codex — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Get Started 3
Portal, sign-up, and the first successful call
Documentation 3
Reference material describing how the API behaves
Agent Surfaces 5
MCP servers, agent skills, and machine-readable catalogs
Design & Contract 6
Pagination, idempotency, versioning, errors, and events
Build 4
SDKs, sample code, and the tooling you integrate with
Access & Security 5
Authentication, authorization, and security posture
Operate 1
Status, limits, changes, and where to get help
Commercial 3
Pricing, plans, and the legal terms of use
Company 2
The organization behind the API
Other 1
Properties that don't map to a standard resource type
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