Surescripts
Surescripts operates the largest health information network in the United States, connecting prescribers, pharmacies, pharmacy benefit managers (PBMs), health plans, and health systems for e-prescribing, medication history, benefit and eligibility verification, electronic prior authorization, and clinical interoperability. Surescripts is a network operator rather than a public API provider - its transaction services run over NCPDP SCRIPT (NewRx, RxRenewal, RxChange, RxTransfer, RxFill, CancelRx), NCPDP Telecommunication, and X12 (270/271 eligibility, 278 prior authorization) standards. There is no self-serve developer portal, no published OpenAPI, and no free API keys; access is gated behind a Surescripts certification process (conformance testing against current NCPDP standards, plus DEA third-party audit for EPCS) or through a certified middleware/EHR partner. The service surfaces below are honestly modeled from Surescripts' published solution descriptions and the underlying NCPDP/X12 transaction standards - endpoints are not publicly documented.
Index entry only — little beyond a description and a link, and nothing machine-readable enough for an agent to act on without a human reading the site first.
API Evangelist profiles Surescripts the way a machine reads it — 7 machine-readable artifacts across 6 APIs, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — Surescripts scores 10.9/100 (minimal), with a separate agent-readiness read of 0/100 (human only). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance.
How we profile Surescripts
Each block below is one kind of artifact we hold for Surescripts. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
APIs 6
Each API is captured as its own OpenAPI definition — every operation, parameter, and response. This is the single most useful machine-readable description of what an API does, and it's what lets us score, lint, mock, and generate against it without asking the provider for anything.
Individual APIs this provider publishes, each with its own machine-readable definition.
Surescripts E-Prescribing
Routes electronic prescriptions between prescribers and pharmacies over the NCPDP SCRIPT standard, supporting NewRx, RxRenewal, RxChange, RxTransfer, RxFill, CancelRx, and NewRx...
Surescripts Eligibility and Formulary
Verifies patient pharmacy benefit eligibility and returns formulary and benefit coverage details so prescribers see coverage and coverage alternatives in workflow. Modeled on X1...
Surescripts Real-Time Prescription Benefit
Returns patient-specific, real-time out-of-pocket drug cost, coverage status, and therapeutic alternatives at the point of prescribing. Modeled on the NCPDP Real-Time Prescripti...
Surescripts Electronic Prior Authorization
Automates electronic prior authorization (ePA) between prescribers and PBMs/payers using the NCPDP SCRIPT ePA transaction set (PAInitiationRequest, PARequest, PAResponse, and re...
Surescripts Clinical Direct Messaging
Provides secure, HIPAA-compliant clinical message exchange (Direct Secure Messaging) for care coordination between providers, including transitions of care and referrals. Delive...
Surescripts Record Locator and Exchange
Locates where a patient has clinical records across the network and enables retrieval of relevant clinical documents to inform care decisions. Delivered to certified participant...
Security Posture 1
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Every other property we hold for Surescripts — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Documentation 1
Reference material describing how the API behaves
Access & Security 2
Authentication, authorization, and security posture
Company 2
The organization behind the API
← All providers · Data indexed from github.com/api-evangelist/surescripts · machine-readable index on apis.io