UniProt
UniProt is the world's leading high-quality, comprehensive, and freely accessible resource for protein sequence and functional annotation data. Maintained by the UniProt Consortium (EMBL-EBI, SIB, and PIR), it integrates information from experimental literature and computational analysis to provide a single authoritative source on protein function, taxonomy, sequences, cross-references, and disease associations. UniProt exposes a REST API at rest.uniprot.org for searching and retrieving entries from UniProtKB, UniRef, UniParc, Proteomes, and supporting services such as ID mapping. All data is freely available under Creative Commons Attribution 4.0.
More than an index entry, but the surface is still mostly links rather than artifacts — the cohort most likely to move a full band from modest, well-targeted work.
API Evangelist profiles UniProt the way a machine reads it — 12 machine-readable artifacts across 7 APIs, pulled from the provider's own public surface and indexed so a developer, an analyst, or an AI agent can evaluate it against every other provider on the network.
Every provider in the network is reduced to the same set of machine-readable artifacts — OpenAPI contracts, event specifications, GraphQL schemas, runnable collections, pricing and rate-limit signals, security posture, OAuth scopes, and the agent surfaces (MCP servers and skills) that let software drive the API on its own. We profile them because the interface is the part of a company you can actually inspect: it is a truer signal of what a provider does than any marketing page. From those artifacts we compute the Kin Score — UniProt scores 26.9/100 (emerging), with a separate agent-readiness read of 24/100 (agent aware). The full breakdown is below, followed by every artifact we hold — each card links through to its machine-readable definition on apis.io.
Kin Score
This is the API Evangelist rating — a single, repeatable read computed from the artifacts on this page. Green fill is points earned; the red track is points possible, so every bar shows earned-versus-possible at a glance.
Kin Score
How this is scored →scored 2026-07-27 · rubric v0.5
How we profile UniProt
Each block below is one kind of artifact we hold for UniProt. For each we say what it is and why it earns a place in the profile, then list every one we've indexed — capped at two rows, scroll within the panel for the rest.
APIs 7
Each API is captured as its own OpenAPI definition — every operation, parameter, and response. This is the single most useful machine-readable description of what an API does, and it's what lets us score, lint, mock, and generate against it without asking the provider for anything.
Individual APIs this provider publishes, each with its own machine-readable definition.
UniProtKB REST API
Search and retrieve protein entries from UniProtKB, which integrates Swiss-Prot (manually reviewed) and TrEMBL (computationally annotated) databases. Supports full-text and fiel...
UniRef REST API
UniRef (UniProt Reference Clusters) groups similar sequences to reduce redundancy. UniRef100 combines identical sequences; UniRef90 clusters sequences sharing 90% identity; UniR...
UniParc REST API
UniParc (UniProt Archive) is a comprehensive non-redundant database of publicly available protein sequences. Each unique sequence appears once with a stable UniParc identifier a...
Proteomes REST API
Provides access to UniProt proteomes — the complete or near-complete sets of proteins from fully sequenced organisms. Supports retrieval of reference proteomes and gene-centric ...
ID Mapping REST API
Maps identifiers between UniProt accessions and over 150 external database identifiers (e.g., RefSeq, Ensembl, PDB, ChEMBL, KEGG, OMIM). Asynchronous job-based service: submit a...
UniProt SPARQL Endpoint
A standards-compliant SPARQL 1.1 endpoint exposing the full UniProt knowledge graph as RDF. The current release contains approximately 232 billion triples across 21 named graphs...
EBI Proteins REST API
The EMBL-EBI Proteins API provides integrated access to UniProt protein annotations alongside large-scale study data including variation data from 1000 Genomes, ClinVar, ExAC, C...
Scroll within the panel for all 7 ·
Pricing Plans 1
Pricing is part of the interface. Machine-readable plans tell you what a tier costs and includes before you commit — one of the six things the Kin Score reads for commercial clarity.
Published pricing tiers and plan structures.
Free
PLANSRate Limits 1
Rate limits are the difference between a demo that works and a production integration that doesn't fall over. Publishing them is an operational-transparency signal — and a hard requirement for any agent that plans its own throughput.
Documented rate limits and quota policies.
Default
RATE LIMITSFinOps 1
Cost, billing, and metering signals let a buyer model the financial operations of an API before it's live. We profile them for the same reason we profile pricing: the money is part of the contract.
Cost, billing, and metering signals for API financial operations.
Overview
FINOPSSemantic Vocabularies 1
JSON-LD contexts give the data shared meaning across APIs. We profile them because semantics are what let a machine reconcile 'customer' here with 'customer' somewhere else.
JSON-LD contexts and semantic vocabularies used across these APIs.
Apis Context
JSON-LDSecurity Posture 1
Authentication, domain security, vulnerability disclosure, and trust-center signals — the evidence that a provider takes security seriously enough to document it. We profile it because you can't govern what you can't see.
Authentication, domain security, vulnerability disclosure, and trust-center signals.
Resources
Every other property we hold for UniProt — documentation, portals, status pages, policies, and corporate surface — grouped by the job it does, following the integrator's arc from getting started to running in production.
Access & Security 1
Authentication, authorization, and security posture
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